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What’s happening in NF1 research today
An Exclusive Interview with Dr. Francis Collins on 10 Years of Advancing NF1 Research through NTAP’s Francis S. Collins Scholars Program
In this exclusive interview, Dr. Francis S. Collins, renowned geneticist and former Director of the National Institutes of Health, reflects on the impact of the Francis Collins Scholars (FCS) Program for Neurofibromatosis Type 1 (NF1) […]
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The Impact of Mentorship and Collaboration in NF1 Research: An Interview with Dr. Shruti Garg and Dr. Steven Rhodes
Over the past ten years, the Francis Collins Scholars (FCS) Program has had a transformative impact on the careers of early-career researchers in the field of neurofibromatosis type 1 (NF1) and related disorders. In interviews […]
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A Decade Of Impact The Francis Collins Scholars Program Is Driving The Future Of Nf1 Research
Baltimore, MD – In 2014, the Francis S. Collins Scholars Program (FCS) in Neurofibromatosis Clinical and Translational Research was launched to transform the landscape of NF1 research by attracting top clinician-scientists into the field. Named […]
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NTAP’s Innovative Funding Approach Delivers Results
NTAP’s innovative funding approach was featured in an article,”Pedal to the Metal” on Inside Hopkins, the Johns Hopkins Medicine daily publication highlighting exceptional and impactful programs. “How an innovative funding approach is advancing research and […]
Read MoreRas Signaling Gone Awry: New Research Published on the Role of Ras in Cutaneous Neurofibroma Pathogenesis
The first manuscript from the NTAP 2022 Cutaneous Neurofibroma Symposium was published digitally by the Journal of Investigative Dermatology today. The paper RAS Signaling Gone Awry in the Skin: The Complex Role of RAS in […]
Read MoreThe 2022 Cutaneous Neurofibroma Symposium
A forum to identify priorities and advance the field of neurofibromatosis type-1 (NF1) research Introduction to NTAP symposiaNTAP convenes leading researchers and innovators from across multiple fields and scientific backgrounds in regular symposia to establish […]
Read More2021 Francis S. Collins Scholars Program in Neurofibromatosis Clinical and Translational Research Award Recipients Named
The Neurofibromatosis Therapeutic Acceleration Program (NTAP) at the Johns Hopkins University School of Medicine is proud to announce that Dr. Nicole Brossier, Dr. Suganth Suppiah, and Dr. Harish Vasudevan have been selected as the 2021 […]
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FDA Approves First Therapy for Children with Debilitating and Disfiguring Rare Disease
For Immediate Release: April 10, 2020 Today, the U.S. Food and Drug Administration approved Koselugo (selumetinib) for the treatment of pediatric patients, 2 years of age and older, with neurofibromatosis type 1 (NF1), a genetic […]
Read MoreUS Breakthrough Therapy Designation in neurofibromatosis type 1 granted by the FDA for the MEK1/2 inhibitor Selumetinib
On April 1, 2019, AstraZeneca (the maker of selumetinib) announced that the US Food and Drug Administration (FDA) granted Breakthrough Therapy Designation (BTD) for the MEK 1/2 inhibitor selumetinib for the treatment of paediatric patients aged three […]
Read MoreSelumetinib in Children with Inoperable Plexiform Neurofibromas
N Engl J Med 2020; 382:1430-1442 DOI: 10.1056/NEJMoa1912735 List of authors. Andrea M. Gross, M.D., Pamela L. Wolters, Ph.D., Eva Dombi, M.D., Andrea Baldwin, P.N.P., Patricia Whitcomb, R.N., Michael J. Fisher, M.D., Brian Weiss, M.D., […]
Read MoreSelumetinib: The First Effective Treatment for Plexiform Neurofibromas
A young patient with NF1 who was treated at NCI gathers with her mother and members of NCI’s Pediatric Oncology Branch. Credit: National Institutes of Health Over 30 years of NCI-led and NCI-supported research culminated […]
Read MoreKoselugo (selumetinib) approved in US for paediatric patients with neurofibromatosis type 1 plexiform neurofibromas
News Release Regulatory News Service 13 April 2020 07:00 BST First medicine approved to treat this rare and debilitating genetic condition AstraZeneca and MSD Inc., Kenilworth, N.J., US (MSD: known as Merck & Co., Inc. […]
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