Neurofibromatosis type 1 (NF1) Data
Radical transparency for faster therapeutic discovery.
Data for all NTAP-funded projects is publicly available through the NF Data Portal, hosted on Synapse. The NF Data Portal was created to help researchers across the field of NF openly explore and share datasets, analysis tools, resources, and publications related to neurofibromatosis and schwannomatosis.
experimental data files across 38 projects with data
projects have data pending
processed or raw datasets
NTAP funded projects have data released
NF1 Data Portal visitors from 69 countries an 16,839 total views (May 1 – Oct 31, 2023)
NTAP files requested (Sep 2022 – Oct 2023)
growth in month-over-month downloads (Sep 2022 – Oct 2023)
51 types of data included in the NF Data Portal
Genome Data
-136 whole genome patient samples; 147 whole exome patient samples
-19 whole exome samples from patients submitted to cBioPortal
-28 matched tumor and blood/unaffected tissue set being prepped for submission to cBioPortal
RNA Data
-147 bulk RNAseq; approximately 655 samples
Data is shared through traditional means of publication and presentation, as well as sharing of raw data.
NF Research Tools Central
NF Research Tools Central is a database that aims to support the development of a robust research toolkit and lower the barrier of entry to neurofibromatosis (NF) research. The database includes NF-associated animal models, cell lines, antibodies, and genetic reagents and details on tool characteristics and sourcing, as well as observational and experimental data.